I have Paint Shop Pro (which is actually owned by Corel now)... An application to use really wasn't the question.
I am specifically asking about which Lossless file formet would be best for subsequent image manipulation. I can have them save in Lossless JPEG (4300 X 3200 image is ~26 MB) or TIFF (same image is ~30MB).. I don't know how large PSD at that resolution is. These are not Layered images and they do not need to be. I do not need to edit the image except for cropping, resizing and optimizing. With Paint Shop Pro, I can take the same Lossless JPEG and save it with relative clarity at the sizes I needed...
For example, look at
www.returnofwhitebuffalo.com, both the painting in the header and the book cover are two such images that I was given at large resolutions. Both came from 25 MB files or so and I was able to reduce them significantly with Paintshop Pro.
So the question at hand is will I get better results from an image format other than Lossless JPEG? File size doesn't matter. All file exchanges are done on Rewriteable CDs and I only get a few images at a time, around a dozen or so.
p.s. Microsoft Paint will not load these files. It doesn't understand Lossless JPEG.