A probable cause for this could be the use of (external) images in posts (including avatars, etc) which are located on a very slow host.
This could explain why some threads are slow loading and others not. Try to find out if you can isolate 1 user that posted in all slow threads, that might lead you to solving this.
I don't think this is a database problem.
It might have something to do with the unserialize bug, but my guess is that you would suffer more from this problem then.
PS that thread loaded fine for me.
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