[Dave]

Something like this should work:

PHP Code:

$handle = fopen("road.txt", "r");
if ($handle) {
    while (($line = fgets($handle)) !== false) {

        $t = explode(",", $line);
        if(isset($t[0]) && strpos($t[0], "London") === false){

            $road = trim($t[0]);

            // Use $road.

        }
    }
    fclose($handle);
}