I'd also be interested to hear the latest.
I remember a little while back I tested it on vBulletin but the only thing I remember was it seemed to totally screw up Google Analytics, which I kind of find humerous. You'd think they would play well together but they didn't.
Everytime Pagespeed would serve a page (maybe for the first time I'm not sure) it would show upwards of 15 plus connections on the same file. I only had it running for a short time (about 6 hours) because I did not see much improvement in speed at all, actually a degradation in most cases. I do remember there being a few quirks with it also but for the life of me I can't remember exactly what they were. I do know at the time it caused of few pages of vbulletin not to render at all especially when being served for the first time but I didn't try and diagnose the issues at the time since it was an active site I was testing on. At the time most of the pages that were rendering were actually taking longer to load then without Pagespeed.
I personally use x-cache on my server which works great with vB. I would be willing to try Pagespeed again if I could hear some more feedback.
From what little experience I had with it, I think if you don't have an overloaded or underpowered server already your benefits with Pagespeed on a vB site will be negligible.
I hope to hear/see someone prove me wrong though!
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