Our site hasn't been launch. But we integrated vbulletin and Horde imp webmail, both using 1 msql db. We use mysql auth with qmail-mysql patch which hasn't kept up with the courier-imap upgrades. Mysql, as I was told by Horde can be replicated on other servers and sync if additional servers are needed and even across several clusters. But it will be much slower than ldap.
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