I changed it in the middle of the day and didn't worry about server loads. Of course, if I had seen something immediately happen, I would have switched back, but I just can't imagine why something so intensive would happen.
The Admin CP thing only affects me because I would very often login to my admin cp to help users here and then a few hours later, logon to the main part of my site and miss everything that had changed up to the time since I had logged into my admin cp cuz the inactivity method would have marked all threads read for me. It's probably something that doesn't affect many users at all.
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