That is a difficult thing to do. vbulletin itself does not have any mailing system, nor does it give any functionality to define what replyto email address should be used. It just uses your servers php mailing function, without giving any parameters to it.
You can however use a different email address to send subscriptions from.
subscriptions@symptome.ch for example. But still replies to those emails are likely to go to
user@domain.com, depending on how your server is configured. In any case they will go to the main email account on the server.
Please take note that you should not use a different domain than the domain you are sending from / your server is configured on. Otherwise large email providers may mistake you for a spammer.